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In the course of this research, Holst and his colleagues established by 1987 that food consumption stimulated the secretion of both GLP-1 and GLP-2

Surgery changes your body to help it make more GLP-1 Medication gives you a synthetic version to help boost levels And when that natural boost from surgery starts to fade, meds can step in and keep things going

GLP-1s are preferred because they have a lower risk of hypoglycemia and a greater potential for weight loss

Scirica BM, Bhatt DL, Braunwald E, Steg PG, Davidson J, Hirshberg B, Ohman P, Frederich R, Wiviott SD, Hoffman EB, Cavender MA, Udell JA, Desai NR, Mosenzon O, McGuire DK, Ray KK, Leiter LA, Raz I, Committee S-TS, and Investigators